I originally started with that sort of stuff in Yojimbo. Sync was not an option though so I switched to Evernote for about a year. I hated having stuff in the cloud and even Evernote's encryption was problematic. I kept searching for something else but not finding anything that would work for me.
Originally Posted by molves
When DEVONThink came out with DEVONThink To Go aka DTTG, I jumped ship. Sync issues have been difficult to work with, due to Apple's policy on limiting the number of beta testers for iPod/iPad/iPhone apps it basically was released in the wild as rough beta SW and very buggy but it is improving fast and I am confident enough of its capability to have switched entirely.
Biggest advantage to me is no need for cloud services. Robust index and search of my database, potential for large datasets and also ability to index and therefore search large sets of files I have on my Mac. It's also very scriptable and so you can do a lot with it via AppleScript if the built in functions are not good enough.
Oogie McGuire - Mac, iPhone & Omnifocus
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Paonia, CO USA