Glad to see this thread - I started another one along the same lines. I use it as an adjunct to my paper system. Mostly for errands, but also for stupid little things I want to remember within the course of a day.
I use it in conjunction with Siri (although I'm still having hilarious issues with Siri understanding me!) and I LUUURRRV the location-based reminders.
I am NOT, however, syncing it with Outlook, nor am I using it as my sole list manager. Still, can't wait to see the set-up guide!