My friend and I have written a series of articles on how to get the most out of Omnifocus. You can find it here:
The program does have a steep learning curve so grab any resources you can to learn the program. However, once you have a good grasp of it, it's amazing. It does take a lot of time and experimentation to see what style of usage fits you, so don't be afraid to carve out some weekends to experiment. Hopefully some of our tutorials can help you. And for any questions, just ask away in this thread.