On the email front: if you feel it would be best to have all in one place, can you set up via POP3 or somesuch so that it all goes into the one email client?

It sounds like you need to be really clear on your areas of focus. While you need to have a way to make sure you're across everything in each area of focus, my experience is that you still want to have everything in the one system - so that you capture it all.