As an attorney, I've faced a similar situation. Each of my clients represents more than a "project" (DA's 10,000 foot level), as each one's case consists of a great number of true projects. However, I wouldn't consider each client to be broad enough to constitute an "area of focus/responsibility" (DA's 20,000 foot level).
I've tried to deal with this by creating what I call a 15, 000 foot level. On my Palm Memo App., I have a category titled 15K-Caselist, which is a list of all of my clients. Within the memo for each client, I've entered revelent information that I might want to have handy.
Then my Project list is reserved for the projects on each file (i.e., serve discovery in Jones case, get expert review for Smith file, etc.).
I have a reminder to "review 15K-Caselist" for each weekly review, so I don't lose anything.