I've been looking at the video demos for Time Matters (www.timematters.com), and I've ordered the software demo so that I can try it out. So far, it looks like this would work really well as a GTD implementation. The "Matters" section sounds like projects to me, and the custom tabs for Todo lists looks like it would be excellent for creating/managing action lists. There are also "alerts" which sound the same as ticklers, you can apparently generate todos/events/meetings/etc from email and so on.
So, has anyone here tried this and/or is using this set up themselves? If so, would you mind sharing your thoughts on the pros and cons?