I don't have a PalmPilot, Microsoft Outlook, or any other do-dad. Yet the system still works for me in my "office".
In GTD, David said that even stay-at-home workers and homemakers could use his method, so I put it to the test. In reading the book, I equated office tasks to home tasks.
I notice that I have some of the same problems as others have mentioned, such as figuring out how to sub-group projects and fighting the temptation to list more than one next action for a project at a time.
One aspect of homemaking that isn't found in the corporate realm is handling the variability that comes with living in your office. Someone in a cubicle or even a private office has only a few ways for something to land in your inbox: telephone, mail, meeting, etc. At home, these avenues are present also, but add to that what you may see when you happen to glance into a room as you walk by. I've found that I have to keep my "inbox" (a small notebook) near me all the time to jot down tasks that suddenly come up and ideas.
Another difference is that the office worker works all day and then stops, closes the books, and goes home. How does one handle always being at work? The inbox is always open.
My biggest pothole is figuring out how to take care of daily tasks with unpredicable time requirements. Doing dishes takes more than two minutes and is more than one step, but good grief, I'm not going to put it on my Projects list. Has anyone had a similar experience in the corporate realm of daily tasks with unpredictable time requirements? How was it conquered?