I had no problem with 2006 but have not yet set it up on my server, for syncing with my laptop. The server is not the machine the laptop is, so I am hoping against hope. My purpose in upgrading was to make the synch process easier. should know this week if I am successfuly! We are not syncing with quickbooks though we use it for accounting. US version even then, so can't help you there. Ram at 384 is not enough. My laptop is running well at 1 gig, so you should not have any trouble.